Your Path to Parenthood™ Starts Here

The next breakthrough in fertility isn’t another treatment, it’s understanding your body better. OTO Fertility decodes how stress affects your system to reveal your Fertility Zone, the state where conception is most likely.

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Redefining What’s Possible in Reproductive Care

OTO Fertility is transforming fertility care by combining stress biology, precision diagnostics, and continuous support. As the first predictive, clinical-grade fertility diagnostic, OTO gives patients and their care teams the clarity and control to move confidently along the Path to Parenthood™.

Capture over 50 real-time body signals through a simple daily assessment with the OTO Fertility device.

Our proprietary algorithm translates your biometric data into a clear, actionable fertility score that reflects your body’s readiness for conception.

Receive daily insights and evidence-based recommendations designed to help you achieve and maintain your optimal Fertility Zone.

Hear From Others

All Testimonials

Life Changing Success

38-year-old Female

“I recognize others haven’t been so lucky with their first transfer working, but my attitude would be the same; all you can do is try. OTO Fertility helped me manage my stress and kept me on track. It kept me focused on my goals and was routine when everything else was up in the air.”

Life Changing Success

35-year-old Female

“I am so happy to have OTO Fertility. It truly keeps me on track and motivated to manage my stress and exercise.

Understanding the OTO Fertility Product & Process

OTO Fertility integrates seamlessly into your care journey, supporting you and your clinic team at every stage. Available exclusively through partner fertility clinics, OTO Fertility ensures that every insight is delivered with the highest level of medical oversight and individualized care.

How it works

The OTO Fertility Biosensor

A clinical-grade Biosensor that tracks stress and fertility biomarkers in real time. Administered and monitored through your clinic, the biosensor ensures that every data point directly supports your personalized fertility treatment plan.

OTO Cira™

Introducing the world’s first wrist-worn Biosensor designed to predict fertility success with clinical-grade accuracy, expanding access to OTO Fertility’s predictive technology in an even more convenient form.

 

Coming in 2026

The OTO Life App

Your secure digital hub for your daily Fertility Index, insights, stress-regulation tools, and progress tracking. Designed to work hand-in-hand with your doctor, the app gives both you and your care team a unified view of your body’s signals and next steps.

OTO Insights™

Our proprietary algorithm transforms complex biometrics into clear, actionable guidance. By integrating directly with your clinic, OTO Fertility removes the guesswork and aligns every recommendation with professional care.

The Technicals

Sensing & Monitoring

Biomarkers Tracked

Captures ECG signals from the chest and wrist and EEG readings from electrodes on the thumb base and forehead to measure autonomic and central nervous system activity.

Signal Precision

Records ECG at >500 Hz, providing high-resolution waveform data (P, Q, R, S, T segments) and precise R–R interval analysis.

Fertility & Stress Indicators

Combines Heart Rate Variability (HRV) and Amplitude-Frequency Analysis (AFA) to assess stress levels, adaptive capacity, oxidative stress, and hypoxia.

Analytical Strengths

Comprehensive Metrics

Generates 20+ validated physiological parameters reflecting autonomic regulation through statistical, spectral, and non-linear methods.

Global Standards

Applies Western HRV standards and Soviet-developed metrics correlated with reproductive health outcomes.

Regulatory & Quality Compliance

FDA Cleared

Built with FDA-certified components and cleared as medical-grade diagnostic hardware.

Manufacturing Controls

Produced in facilities certified under ISO 9001:2015 and ISO 13485:2016, ensuring full traceability, risk management, and quality system oversight for medical devices

Clinical Edge

Unlike optical sensors, OTO’s ECG-based system detects cardiac and stress dysfunctions often missed by HRV-only wearables, enabling real-time insight into stress resilience and readiness.

Functional Role

Purpose

Extends OTO’s electrophysiological monitoring to a wrist form factor for everyday wear and continuous use.

Integration

Works in sync with OTO Life App and OTO Insights to capture ECG, HRV, and EEG-derived signals throughout fertility and pregnancy.

Diagnostic Framework

Proprietary Algorithms

Employs the same patented models as the Biosensor to evaluate autonomic and CNS balance, stress resilience, and adaptive capacity.

Unified Methodology

Maintains consistent medical-grade accuracy under the same clinical framework.

Regulatory & Quality Compliance

FDA Cleared

Certified for medical-grade physiological monitoring under FDA review.

ISO Manufacturing

Hardware manufactured under ISO 9001:2015 and ISO 13485:2016 quality management standards, ensuring precision assembly and process control.

Unified Data Hub

Connectivity

Pairs with OTO Biosensor and Cira to display live ECG, HRV, and EEG-derived direct-current (DC) potential data.

Data Integration

Consolidates multiple physiological streams into a single dashboard for clinicians and users, supporting continuous reproductive health monitoring.

Key Insights

Metrics Displayed

Stress level, functional reserve, adaptive capacity, readiness for exertion, and neuroendocrine balance.

Clinical Utility

Provides dynamic visualization of CNS and ANS responses during fertility treatment and pregnancy.

CNS Profiling

DC Potential Tracking

Measures EEG-derived DC potential (0–0.5 Hz) to interpret CNS activation and regulatory tone.

Functional Insights

Identifies mental readiness, stress resilience, and energy expenditure to assess neurofunctional efficiency.

Data Protection & Security

HIPAA Compliant

All collected data is encrypted, anonymized, and managed in accordance with U.S. HIPAA laws to safeguard patient privacy.

End-to-End Security

Uses secure transmission protocols and restricted database access to protect health information during storage and transfer.

Data Intelligence

Algorithmic Processing

Synthesizes ECG and EEG data through 50+ proprietary algorithms, analyzed across six statistical dimensions (mean, median, trend, variance, SD, CV).

Validation Framework

Applies paired t-tests and Wilcoxon signed-rank tests to ensure signal significance and data integrity.

Predictive Modeling

Feature Mapping

Produces 1,900+ physiological features per user across six IVF cycle phases to forecast fertility success and pregnancy probability.

Machine Learning

Identifies key biomarker combinations predictive of adaptive efficiency and reproductive health outcomes.

Clinical Application

Integrated Monitoring

Correlates CNS, ANS, and cardiac signals to detect stress and neuroendocrine imbalance.

Treatment Optimization

Provides clinicians with personalized insights to improve IVF timing, reduce risk factors, and enhance prenatal care.

Frequently Asked Questions

  • What makes OTO Fertility different from other products?

    OTO Fertility isn’t just another app or tracker; it’s a clinical-grade diagnostic system backed by peer-reviewed research and developed in partnership with leading fertility experts. Designed to support both patients and clinics, OTO Fertility provides data-driven guidance from preconception through postpartum care.

  • Is OTO Fertility right for me?

    If you’ve experienced stress, uncertainty, or repeated setbacks on your fertility journey, OTO Fertility was designed to help you regain clarity and control. It works alongside your fertility doctor to improve outcomes and increase IUI and IVF success rates.

  • How do I get started with OTO Fertility?

    OTO Fertility is available exclusively through partner fertility clinics. Use our Find a Clinic tool to connect with a participating clinic near you and begin your personalized care plan.